A New Concept for Hydrochloric Acid Formation.carbonic Anhydrase Isoenzymes Implications

Absract The collective of Professor Puscas sugests a theory The pH theory, which presents as a common element of these three receptors (for histamine, acetylcholine and gastrine)the carbonic anhydrase. According to this theory histamine, gastrine and acetylcholine have a dual effect on the parietal cell: one known, that their specific receptor binding, and the second effect, that the activation of CA IV, discovered by Professor Puscas. The results suggest that activation of CA IV, by releasing of H, produces changes in pH, necessary histamine, acetylcholine and gastrine binding to specific membrane receptors. In this case, histamine the final common path according to Grossman's theory and Code theory have as common element the CA IV in parietal cell membranes, under pH theory.